Twisynt Technologies Pvt Ltd: Enhancing CKD Management Through Continuous Potassium Monitoring

Twisynt Technologies Private Limited, founded by Vismaya S, is a Bengaluru-based medtech company developing advanced solutions for renal health monitoring. Operating from MSMF, Mazumdar Shaw Medical Center, Hosur Rd, Bommasandra Industrial Area, Bengaluru, the organization is currently focused on TinySense, a wearable engineered to provide real-time, non-invasive potassium monitoring for individuals with Chronic Kidney Disease (CKD) and those undergoing dialysis.

Clinical Context: Potassium Instability in CKD

Potassium dysregulation is a well-recognized complication in CKD, often resulting from diminished renal excretion, dialysis intervals, comorbidities, and medication interactions. Acute hyperkalemia or hypokalemia can lead to:

• Life-threatening arrhythmias

• Conduction abnormalities

• Sudden cardiac arrest

• Emergency hospitalization

Standard laboratory testing offers intermittent data, which may not adequately capture intra-day potassium fluctuations. This intermittent visibility leaves patients vulnerable to rapid electrolyte shifts between clinical visits.

TinySense: A Non-Invasive Approach to Real-Time Electrolyte Monitoring

TinySense is designed to provide continuous potassium trend data without blood sampling, offering a more comprehensive understanding of the patient’s biochemical status.

Key Medical Advantages

• Continuous physiological monitoring
Provides dynamic potassium trend analysis, allowing early recognition of potentially dangerous deviations.

• Non-invasive sensing technology
Eliminates the discomfort and limitations associated with frequent blood draws, improving adherence and patient comfort.

• Early alerts for clinical intervention
Pre-symptomatic notification helps clinicians intervene before electrolyte imbalance escalates.

• Supports individualized care plans
Trend-based insights can aid nephrologists in adjusting dialysis prescriptions, dietary recommendations, and medication dosing.

• Reduced emergency events
Improved surveillance may decrease hospitalization rates related to acute potassium imbalance.

Relevance in CKD and Dialysis Care

CKD patients experience frequent fluctuations in potassium due to variable renal function, dietary intake, fluid shifts, and dialysis timing. A continuous monitoring system can significantly improve clinical stability by:

• Identifying high-risk trends early

• Reducing dependency on episodic testing

• Enhancing safety during inter-dialytic periods

• Supporting clinical decision-making with real-time data

TinySense aligns with current nephrology goals of predictive, proactive care.

Leadership Focused on Clinical Impact

Under the guidance of Founder & Director Vismaya S, Twisynt Technologies is focused on developing clinically validated, patient-centric devices that address high-priority challenges in renal care. The team integrates expertise from biomedical engineering, sensor research, and nephrology-aligned innovation.

Location

Office / R&D Facility:
MSMF, Mazumdar Shaw Medical Center
Hosur Rd, Bommasandra Industrial Area
Bengaluru, Karnataka 560099

Website: twisynt.com